Blar i NTNU Open på forfatter "Mahammad, Nur"

Viser treff 1-4 av 4

    • cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation 

      Ashcroft, Felicity; Mahammad, Nur; Flatekvål, Helene Midtun; Feuerherm, Astrid Jullumstrø; Johansen, Berit (Journal article, 2020)
      As a regulator of cellular inflammation and proliferation, cytosolic phospholipase A2 α (cPLA2α) is a promising therapeutic target for psoriasis; indeed, the cPLA2α inhibitor AVX001 has shown efficacy against plaque psoriasis ...

    • Inflammasome Activator Nigericin Induces Apoptosis in Myeloma cells 

      Mahammad, Nur (Master thesis, 2015)
      Multiple myeloma (MM) is a neoplastic disorder of plasma cells. Research has shown that cytokines act as a double edged sword in tumour microenvironment to facilitate MM cell homing, survival, proliferation and pathogenesis. ...

    • Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells 

      Mahammad, Nur; Ashcroft, Felicity; Feuerherm, Astrid Jullumstrø; Elsaadi, Samah; Vandsemb, Esten Nymoen; Børset, Magne; Johansen, Berit (Peer reviewed; Journal article, 2021)
      Cytosolic phospholipase A2α (cPLA2α) is the rate-limiting enzyme in releasing arachidonic acid and biosynthesis of its derivative eicosanoids. Thus, the catalytic activity of cPLA2α plays an important role in cellular ...

    • Targeting Cytosolic Phospholipase A2 alpha (cPLA2α) in Hematological Cancers and Inflammation 

      Mahammad, Nur (Doctoral theses at NTNU;2023:409, Doctoral thesis, 2023)
      Cytosolic phospholipase A2 alpha (cPLA2α) is an enzyme that plays a crucial role in regulating the balance between cellular growth and death by releasing the unsaturated fatty acid arachidonic acid from membrane lipids. ...